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Clinical, electrophysiological, and serological overlap between Miller Fisher syndrome and acute sensory ataxic neuropathy
Author(s) -
Shimamura H.,
Miura H.,
Iwaki Y.,
Kubodera T.,
Matsuoka T.,
Yuki N.,
Koga M.
Publication year - 2002
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1034/j.1600-0404.2002.01144.x
Subject(s) - ataxia , medicine , sensory system , miller fisher syndrome , autoantibody , peripheral neuropathy , polyneuropathy , cerebellar ataxia , serology , neuroscience , pathology , immunology , antibody , psychology , endocrinology , diabetes mellitus , psychiatry
We report a patient with severe sensory ataxia, areflexia, and ophthalmoplegia with preservation of limb muscle strength. Electrophysiological examinations revealed peripheral sensory nerve involvement. A serological examination showed the elevation of IgG antibodies to various b‐series gangliosides as well as GT1a. These indicated that this case is an overlap between acute sensory ataxic neuropathy and Miller Fisher syndrome. Autoantibody is implicated as potential pathogenic agents in some cases of acute sensory ataxic neuropathy.