Premium
Diffusion‐weighted MR findings of central pontine and extrapontine myelinolysis
Author(s) -
Chu K.,
Kang D.W.,
Ko S.B.,
Kim M.
Publication year - 2001
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1034/j.1600-0404.2001.00096.x
Subject(s) - pons , central pontine myelinolysis , corpus callosum , effective diffusion coefficient , medicine , diffusion mri , edema , diffusion , magnetic resonance imaging , midbrain , pathology , radiology , central nervous system , physics , thermodynamics
Diffusion‐weighted MR (DWI) can detect changes in water diffusion associated with cellular dysfunction, which enables the differentiation of cytotoxic edema from vasogenic edema. In this study on DWI findings in central pontine (CPM) and extrapontine myelinolysis (EPM), DWI showed high signal intensities in the bilateral pons, midbrain, and genu of the corpus callosum. The corresponding apparent diffusion coefficient values were rather low. This suggests that cytotoxic edema does in fact exist in CPM and EPM and that DWI can be useful in the rapid diagnosis and prediction of the various types of edema occurring in active demyelinating diseases.