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Epilepsia partialis continua in Creutzfeldt–Jakob disease
Author(s) -
Lee K.,
Haight E.,
Olejniczak P.
Publication year - 2000
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1034/j.1600-0404.2000.102006398.x
Subject(s) - epilepsia partialis continua , dementia , electroencephalography , right hemisphere , epilepsy , medicine , neuroscience , disease , lateralization of brain function , psychology , audiology , pathology , status epilepticus
Objectives – We describe a patient with Creutzfeldt–Jakob disease (CJD) with epilepsia partialis continua (EPC) and complex partial seizures. Material, methods and results – The patient presented with semi‐rhythmic jerking movements of the right upper extremity. Serial EEG findings showed progressive changes with initial periodic lateralizing epileptiform discharges (PLEDs) on the left hemisphere which evolved into more generalized periodic sharp wave complexes (PSWCs) at later stage. Video‐EEG monitoring recorded complex partial seizures originating from the left hemisphere in addition to EPC. Conclusions – A diagnosis of CJD should be considered when a rapidly progressive dementia is accompanied by abnormal movements. EPC, although rare, may present as an initial manifestation of CJD.