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A randomised double‐blind evaluation of adenosine as adjunct to sufentanil in spinal labour analgesia
Author(s) -
Rane K.,
Sollevi A.,
Segerdahl M.
Publication year - 2003
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1034/j.1399-6576.2003.00110.x
Subject(s) - sufentanil , medicine , anesthesia , intrathecal , adenosine , pain relief
Background: Intrathecal injection of sufentanil offers labour pain relief of short duration. This double‐blind randomised study evaluates if the combination of adenosine to sufentanil could give relevant prolongation (40%) of the duration of sufentanil spinal analgesia. Methods: Twenty‐five healthy parturients requesting labour analgesia were included. Patients received 10 µg of sufentanil + 500 µg of adenosine or 10 µg of sufentanil intrathecally. Pain intensity and duration of pain relief were assessed. Results: Pain relief was equal between groups. Duration of analgesia was not increased by adenosine + sufentanil, 99 ± 54 min, vs. sufentanil, 89 ± 56 min. Conclusion: Adding 500 µg of adenosine to 10 µg of sufentanil could not provide any prolongation of labour pain relief.