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Use of an EEG‐bispectral closed‐loop delivery system for administering propofol
Author(s) -
Sakai T.,
Matsuki A.,
White P. F.,
Giesecke A. H.
Publication year - 2000
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1034/j.1399-6576.2000.440819.x
Subject(s) - propofol , bispectral index , medicine , anesthesia , sedation , sedative , hypnotic , remifentanil , continuous infusion , electroencephalography , closed loop , psychiatry , control engineering , engineering
Closed‐loop control of propofol delivery was instituted in three patients who received a propofol infusion as part of: (Case 1) general “balanced” anesthesia, (Case 2) total intravenous anesthesia, and (Case 3) monitored anesthesia care. The bispectral index was the input variable used in a proportioned, integral and differential controller to determine the infusion rate of propofol required to maintain a stable level of hypnosis (Cases 1 and 2) or sedation (Case 3). This feedback control system provided intraoperative hemodynamic stability and a prompt recovery from the sedative‐hypnotic effects of propofol.