Premium
Incidence, prevalence, and mortality of insulin‐dependent (type 1) diabetes mellitus in Lithuanian children during 1983–98
Author(s) -
Urbonaite Brone,
Zalinkevicius Rimas,
Green Anders
Publication year - 2002
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1034/j.1399-5448.2002.30105.x
Subject(s) - medicine , incidence (geometry) , diabetes mellitus , demography , cohort , population , cohort study , type 1 diabetes , type 2 diabetes , pediatrics , endocrinology , environmental health , physics , sociology , optics
Aims/hypothesis: Our purpose is to analyze interrelations of the incidence, prevalence and mortality of childhood‐onset insulin‐dependent diabetes mellitus (type 1) in Lithuania. Methods: Incidence and prevalence rates were based on the national type 1 diabetes register during 1983–98. The cohort study was performed to evaluate the standardized mortality ratios. Results: The average incidence of type 1 diabetes during the 16‐yr study period was 7.36 per 100 000/yr. For both males and females the highest incidence of type 1 diabetes was recorded in the 10–14 yr age group. The regression‐based linear trends of the increase in incidence in various age groups and the annual percentage change for both genders was 2.05 (p = 0.0039) and the greatest regression slope is observed for both genders in the 10–14 yr age group. Regression‐based linear trends in type 1 diabetes prevalence indicate an even growth in all age groups (3.47; p = 0.001), although the annual percentage change is most prominent in the 5–9 yr age group for girls (4.95%/yr) and in the 10–14 yr age group for boys (4.06%/yr). The standardized mortality ratio of all‐cause mortality in people with diabetes is higher than in the common population 7.71 (p < 0.0001). The standard mortality ratio for all causes increases with longer diabetes duration. Conclusion/interpretation: The significant increasing trend of incidence and prevalence during 1983–98 is observed. The annual percentage change is similar. The young patients with type 1 diabetes have a higher mortality risk.