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Use of hypertonic saline in the treatment of cerebral edema in diabetic ketoacidosis (DKA)
Author(s) -
Curtis Jacqueline R,
Bohn Desmond,
Daneman Denis
Publication year - 2001
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1034/j.1399-5448.2001.20409.x
Subject(s) - medicine , diabetic ketoacidosis , cerebral edema , hypertonic saline , tonicity , anesthesia , edema , diabetes mellitus , mannitol , saline , ketoacidosis , surgery , type 1 diabetes , endocrinology , chemistry , organic chemistry
Cerebral edema is the primary cause of morbidity and mortality in children and adolescents with diabetic ketoacidosis (DKA). We report a case of an adolescent female with life‐threatening DKA‐related cerebral edema who responded to a combination of mannitol and hypertonic saline. This is the first report of the use of hypertonic saline in the treatment of cerebral edema due to DKA.