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Efficacy of Aspergillus galactomannan‐directed preemptive therapy for the prevention of invasive aspergillosis in organ transplant recipients
Author(s) -
Marino I.R.,
Panarello G.,
Singh N.
Publication year - 2002
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1034/j.1399-3062.2002.02003.x
Subject(s) - medicine , galactomannan , aspergillosis , intensive care medicine , empiric therapy , antimicrobial , organ transplantation , pathogenic organism , immunology , transplantation , pathology , microbiology and biotechnology , alternative medicine , biology
Editor's comment: This letter from Marino et al. represents confirmation of an important principle: a preemptive antimicrobial strategy based on a reliable laboratory finding is an excellent way to prevent clinical disease due to an important pathogen. We hope this approach can be expanded as useful early diagnostic techniques become more available. It is my belief that a therapeutic prescription based on a laboratory marker is a more robust approach than “empiric therapy,” where therapy is prescribed by algorithm rather than measurable laboratory findings (3). R.H. Rubin, MD