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Economic impact of cytomegalovirus in solid organ transplantation
Author(s) -
Paya C.V.
Publication year - 2001
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1034/j.1399-3062.2001.00003.x
Subject(s) - medicine , cytomegalovirus , cytomegalovirus infections , transplantation , cytomegalovirus infection , solid organ , organ transplantation , intensive care medicine , immunology , human cytomegalovirus , herpesviridae , viral disease , virus
Cytomegalovirus (CMV) infection has a direct effect on morbidity in solid organ transplantation patients, and indirect effects related to the development of opportunistic infections, allograft rejection, and patient mortality. Although intuitively it follows that costs attributable to CMV infections would be increased, direct proof has remained elusive. Accumulating evidence suggests, however, that CMV infection has a significant impact on the costs to transplantation programs, particularly in seronegative recipients of seropositive allografts (D+/R–), and additional costs may be incurred through the effects on CMV potentiating the risks of various opportunistic infections leading to graft rejection.