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Expression of porcine endogenous retrovirus in peripheral blood leukocytes from ten different breeds
Author(s) -
Jin H.,
Inoshima Y.,
Wu D.,
Morooka A.,
Sentsui H.
Publication year - 2000
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1034/j.1399-3062.2000.020103.x
Subject(s) - xenotransplantation , endogenous retrovirus , medicine , virology , peripheral blood , retrovirus , immunology , endogeny , infectious disease (medical specialty) , disease , biology , pathology , virus , gene , genetics , transplantation , genome
The expression of porcine endogenous retroviruses (PERV) was investigated in primary porcine peripheral blood leukocytes (PBL) of ten different pig breeds. The data suggest that PERV exists in all porcine PBL. A new retroviral element, a foamy‐like pol ‐related sequence, was also detected in PBL. Three types of PERV were detected in almost every animal. The breeding of PERV‐free pigs is likely to be difficult. Further studies are required to assess the infectious disease risks associated with xenotransplantation.