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Domino as a bridge to definitive liver transplantation in a neonate
Author(s) -
CasasMelley Adela T.,
Thomas Philip G.,
Krueger Leslie J.,
Falkenstein Kathleen P.,
Flynn Louise M.,
Conley Susan B.,
Dunn Stephen P.
Publication year - 2002
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1034/j.1399-3046.2002.01083.x
Subject(s) - medicine , liver transplantation , fulminant hepatic failure , primary hyperoxaluria , surgery , transplantation , fulminant , portal vein thrombosis , thrombosis
An interim liver transplant was used to extend survival in a neonate. This was accomplished by the initial transplant of a left‐lateral segment of a metabolically abnormal liver obtained from a 7‐yr‐old patient with primary oxalosis. This bridging strategy was required because our neonatal patient was dying of fulminant hepatic failure caused by hepatic vein thrombosis and a small liver or liver segment could not be found. Although problems with hyperoxaluria were encountered in the neonate post‐transplant, the interim liver transplant enabled the baby to survive and grow until the age of 4 months. At that time, a definitive transplant was performed using the left‐lateral segment of his mother's liver. This case represents the first reported use of a pediatric domino transplant where a metabolically abnormal liver was used to allow sufficient growth to permit a definitive liver transplantation.