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Portal vein phlebolithiasis found post‐liver transplantation in the native liver of a child with biliary atresia
Author(s) -
Bilezikçi B.,
Demirhan B.,
Kiyici H.,
Haberal M.
Publication year - 2001
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1034/j.1399-3046.2001.t01-1-00020.x
Subject(s) - biliary atresia , medicine , liver transplantation , gastroenterology , lumen (anatomy) , pouch , atresia , cirrhosis , transplantation , bile duct , biliary cirrhosis , surgery , disease , autoimmune disease
Biliary atresia is defined as partial or total obliteration of the extra‐hepatic bile ducts. In advanced cases, liver transplantation (LTx) is considered the most appropriate treatment. This report describes a female patient whose biliary atresia and subsequent cirrhosis required LTx at 1 yr of age. Macroscopic inspection of the hilar region of the native liver post‐Tx revealed the formation of a pouch in the hepatic duct and a stone in the lumen of the portal vein. X‐ray diffraction analysis showed that the stone was composed of cholesteryl cinnamate, gluconic acid phenylhydrazide, Na β broma‐allyl mercaptomethyl penicillinate, and Al 2 O 3 crystals. While the cholesterol component is a known element of gallstones, we attributed the Na β broma‐allyl mercaptomethyl penicillinate to the patient's drug therapy. Our literature search revealed no previous record or crystallographic analysis of portal vein phlebolithiasis. In this report we describe this rare finding.