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Successful transplantation of a cadaveric kidney with post‐infectious glomerulonephritis
Author(s) -
Mizuiri S.,
Shigetomi Y.,
Sugiyama K.,
Miyagi M.,
Hatano T.,
Tajima E.,
Aikawa A.,
Ohara T.,
Kawamura S.,
Hasegawa A.
Publication year - 2000
Publication title -
pediatric transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 69
eISSN - 1399-3046
pISSN - 1397-3142
DOI - 10.1034/j.1399-3046.2000.00076.x
Subject(s) - medicine , cadaveric spasm , kidney , glomerulonephritis , transplantation , kidney transplantation , proteinuria , renal function , urology , kidney disease , surgery
This report describes a successful renal Tx in a patient with chronic renal failure, caused by dysplastic kidneys, who received a cadaveric kidney with post‐infectious glomerulonephritis. Sequential renal biopsies were performed at 12 h before Tx, and at 1 h and on days 8 and 58 post‐Tx. Post‐operative hematuria disappeared on day 9 and proteinuria on day 13. Normal graft function was observed within 1 month, with histologic resolution. Our study suggests that while the donor kidney facilitates deposition of certain immune reactants, this is a host (environmental) problem and when transplanted into a new host (new environment), the problem is no longer sustained.