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Infant lung function, bronchial responsiveness and the developmentof asthma
Author(s) -
Le Souëf Peter
Publication year - 2000
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1034/j.1399-3038.2000.00504.x
Subject(s) - wheeze , atopy , medicine , asthma , lung function , immunology , allergy , airway , pediatrics , lung , anesthesia
Infants who wheeze are likely to have narrowed or overly compliant airways rather than atopy. After around 3 years of age, airway responsiveness and atopy are associated with the development of wheeze and the diagnosis of asthma. Anti- or proinflammatory genes are likely to be responsible for at least part of the predisposition to wheeze seen in older children, but further studies are needed to clarify this situation.