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Thoracic organ donor characteristics associated with successful lung procurement
Author(s) -
McElhinney Doff B,
Khan Junaid H,
Babcock Wayne D,
Hall Timothy S
Publication year - 2001
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1034/j.1399-0012.2001.150112.x
Subject(s) - medicine , lung transplantation , lung , economic shortage , procurement , organ procurement , referral , surgery , united network for organ sharing , multivariate analysis , lung function , transplantation , intensive care medicine , emergency medicine , family medicine , linguistics , philosophy , marketing , government (linguistics) , business , liver transplantation
Purpose: A shortage of suitable donors is the major impediment to clinical lung transplantation. The rate of lung recovery from potential donors is lower than that for other organs. The purpose of this study was to evaluate what factors could be modified to improve the rate of cadaver lung recovery.
Methods: We performed a retrospective review of records from all thoracic organ donors procured by the California Transplant Donor Network between 1 January 1995 and 31 May 1997 (251 donors) to determine which donor management factors were associated with an increased likelihood of successful lung procurement.
Results: There were 88 lung donors (L) and 163 donors from which hearts but no lungs were procured (H). Longer time to donor network referral was associated with a reduced chance for successful lung procurement. Donor age, cause of death, and time of admission were not important factors. Most donors in this study had an acceptable A‐a gradient at admission to the hospital but lung function deteriorated in group H. Corticosteroid usage and initially clear breath sounds were independent predictors of successful procurement by multivariate analysis.
Conclusions: Early contact with the donor referral network, and corticosteroids may help to improve the lung procurement rate from potential donors.