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Intratubular calcification in a post‐renal transplanted patient with secondary hyperparathyroidism
Author(s) -
Iguchi Seitaro,
Nishi Shinnichi,
Shinbo Junnichi,
Iino Noriaki,
Kazama J Junichiro,
Shimada Hisaki,
Ueno Mitsuhiro,
Saitou Kazuhide,
Tanigawa Toshiki,
Takahashi Kouta,
Gejyo Fumitake
Publication year - 2001
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1034/j.1399-0012.2001.0150s5051.x
Subject(s) - medicine , calcification , tacrolimus , hyperparathyroidism , secondary hyperparathyroidism , kidney transplantation , biopsy , transplantation , calcinosis , adverse effect , kidney , pathology , urology , surgery , calcium , parathyroid hormone
Iguchi S, Nishi S, Shinbo J, Iino N, Kazama JJ, Shimada H, Ueno M, Saitou K, Tanigawa T, Takahashi K, Gejyo F. Intra‐tubular calcification in a post‐renal transplanted patient with secondary hyperparathyroidism. Clin Transplantation 2001: 15 (Supplement 5): 51–54. ©Munksgaard, 2001 In this article, we present a case in which marked intratubular calcification occurred in the transplanted kidney. The patient received living renal transplantation without control of severe secondary hyperparathyroidism, and the tacrolimus hydrate was used as an immunosuppressive agent, the adverse effects of which can induce intratubular calcification. Biopsy of the renal allograft revealed many intratubular calcifications in the cortex region of the specimen, although the histological grade was borderline for the Banff classification. The pathogenic causes of intratubular calcification were difficult to distinguish from the adverse effects of tacrolimus and the uncontrolled hyperparathyroidism.