Premium
Regulation by intracellular glutathione of TNF‐α‐induced p38 MAP kinase activation and RANTES production by human pulmonary vascular endothelial cells
Author(s) -
Hashimoto S.,
Gon Y.,
Matsumoto K.,
Takeshita I.,
Asai Y.,
Asai Y.,
Machino T.,
Horie T.
Publication year - 2000
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1034/j.1398-9995.2000.00455.x
Subject(s) - mitogen activated protein kinase , p38 mitogen activated protein kinases , kinase , map kinase kinase kinase , biology , microbiology and biotechnology , protein kinase a , chemistry
Conclusions: These results indicated that TNF‐α‐induced p38 MAP kinase activation and p38 MAP kinase‐mediated RANTES production by human pulmonary vascular endothelial cells are inversely regulated by intracellular GSH levels.