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Microwave radiation alters peristaltic activity of isolated segments of rat gut
Author(s) -
McArthur Gregory R.,
Lords James L.,
Durney Carl H.
Publication year - 1977
Publication title -
radio science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.371
H-Index - 84
eISSN - 1944-799X
pISSN - 0048-6604
DOI - 10.1029/rs012i06sp00157
Subject(s) - peristalsis , bradycardia , autonomic nervous system , heart rate , small intestine , absorption (acoustics) , chemistry , materials science , biophysics , anatomy , biology , endocrinology , blood pressure , composite material
Irradiation (960‐MHz) of isolated post‐pyloric segments of rat gut at a specific absorption rate (SAR) of 1.5–5.5 W/kg caused an increase in peristaltic activity. A pressure transducer was used to monitor waveforms of muscle movements in a canulated section of intestine. The preparation was suspended in isothermal, aerated, modified Ringer's solution. Microwave radiation was applied with a parallel‐plate capacitor‐type radiator. The SAR was calculated from temperature measurements made with a liquid‐crystal optical‐fiber (LCOF) temperature probe. As reported previously, similar radiation applied to isolated turtle and rat heart caused bradycardia. These effects, in both the heart and gut, are thought to be neurally mediated by the release of transmitter substances by the autonomic nervous system (ANS). Generally, these effects can be modified by the addition of drugs that are effective at synapses within the ANS. In both the heart and gut, sympathetic and parasympathetic effects can be separated by the application of drugs that selectively block one or the other of the two divisions of the ANS.