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Effect of ramipril in a patient with glycogen storage disease type I and nephrotic‐range proteinuria
Author(s) -
Pela I.,
Donati M. A.,
Zammarchi E.
Publication year - 2001
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1023/a:1012715110596
Subject(s) - ramipril , proteinuria , nephrotic syndrome , medicine , urology , excretion , renal function , endocrinology , blood pressure , urinary system , kidney
We studied the effect of ramipril on urinary protein excretion and arterial pressure in a 27‐year‐old patient with GSD Ia and heavy proteinuria (2–3 g/24 h). Ramipril therapy resulted in an important reduction of proteinuria (0.3–0.5 g/24 h): no changes were observed in arterial pressure and renal function during the 12‐month follow‐up. We conclude that treatment with ramipril can be employed effectively and safely in GSD Ia patients with nephrotic‐range proteinuria.