Open AccessNetworking Nanoswitches for ON/OFF Control of Catalysis
Author(s) -
Nikita Mittal,
Susnata Pramanik,
Indrajit Paul,
Soumen De,
Michael Schmittel
Publication year - 2017
Publication title -
journal of the american chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/jacs.6b12951
Subject(s) - chemistry , catalysis , conjugate , copper , ion , catalytic cycle , combinatorial chemistry , photochemistry , organic chemistry , mathematics , mathematical analysis
The nanoswitches 1 and 2 are interdependently linked in so-called network states (NetStates). In NetState I, defined by presence of [Cu(1)] + and 2, the organocatalyst N-methylpyrrolidine catalyzes a conjugate addition. Addition of iron(II) ions as an external chemical trigger to NetState I discharges Cu + from [Cu(1)] + . The liberated copper(I) ion acts as a second messenger and changes the toggling state at nanoswitch 2. The resulting nanoswitch [Cu(2)] + captures the catalytically active species from solution and the conjugate addition is turned OFF. Removal of the original trigger reverses the sequence and turns catalysis ON. The ON/OFF catalytic cycle was run three times in situ.