Open AccessDiscovery of Small-Molecule Allosteric Inhibitors of PfATC as Antimalarials
Author(s) -
Chao Wang,
Bidong Zhang,
Arne Krüger,
Xiaochen Du,
Lidia Visser,
Alexander Dömlingꝉ,
Carsten Wrenger,
Matthew R. Groves
Publication year - 2022
Publication title -
journal of the american chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/jacs.2c08128
Subject(s) - allosteric regulation , chemistry , drug discovery , plasmodium falciparum , small molecule , stereochemistry , affinities , binding site , active site , biochemistry , pharmacology , malaria , enzyme , biology , immunology
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