1,6-epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease
Author(s) -
Ken Kok,
C.J. Kuo,
Rebecca E. Katzy,
Lindsey T. Lelieveld,
Liang Ping Wu,
V. Roig-Zamboni,
Gijsbert A. van der Marel,
Jeroen D. C. Codée,
G. Sulzenbacher,
G.J. Davies,
Herman S. Overkleeft,
Johannes M. F. G. Aerts,
Marta Artola
Publication year - 2022
Publication title -
journal of the american chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/jacs.2c05666
Subject(s) - chemistry , glucosidases , enzyme , biochemistry , in vivo , molecular mimicry , hydrolase , lysosomal storage disease , iminosugar , small molecule , antibody , microbiology and biotechnology , immunology , biology
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