Open AccessReaction Mechanism of Human PAICS Elucidated by Quantum Chemical Calculations
Author(s) -
Mario Prejanò,
Jana Škerlová,
Pål Stenmark,
Fahmi Himo
Publication year - 2022
Publication title -
journal of the american chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/jacs.2c05072
Subject(s) - chemistry , active site , ribonucleotide , tetrahedral carbonyl addition compound , deprotonation , carboxylation , elimination reaction , reaction mechanism , reaction intermediate , concerted reaction , density functional theory , stereochemistry , computational chemistry , nucleotide , combinatorial chemistry , enzyme , catalysis , organic chemistry , ion , biochemistry , nucleophile , gene
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