Open AccessSubstrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome b5
Author(s) -
Yilin Liu,
Ilia G. Denisov,
Stephen G. Sligar,
James R. Kincaid
Publication year - 2021
Publication title -
journal of the american chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/jacs.1c00581
Subject(s) - chemistry , cyp17a1 , allosteric regulation , stereochemistry , substrate (aquarium) , pregnenolone , active site , aminoglutethimide , lyase , enzyme , biochemistry , steroid , oceanography , hormone , geology , medicine , cancer , breast cancer , aromatase
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom