Open AccessPCR-like Cascade Reactions in the Context of an Allosteric Enzyme Mimic
Author(s) -
HoGeun Yoon,
Chad A. Mirkin
Publication year - 2008
Publication title -
journal of the american chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/ja804076q
Subject(s) - chemistry , allosteric regulation , cascade , supramolecular chemistry , catalysis , context (archaeology) , cascade reaction , enzyme , enzyme catalysis , combinatorial chemistry , ion , allosteric enzyme , stereochemistry , organic chemistry , chromatography , molecule , paleontology , biology
A supramolecular allosteric catalyst that exhibits a PCR-like cascade reaction is reported. The complex is triggered by a reaction with an acetate ion, which turns on a catalytic cascade that exponentially increases acetate ion concentration through an acyl transfer reaction.