Open AccessCobalt-Catalyzed C–H Borylation
Author(s) -
Jennifer V. Obligacion,
Scott P. Semproni,
Paul J. Chirik
Publication year - 2014
Publication title -
journal of the american chemical society
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 7.115
H-Index - 612
eISSN - 1520-5126
pISSN - 0002-7863
DOI - 10.1021/ja500712z
Subject(s) - chemistry , borylation , cobalt , catalysis , inorganic chemistry , organic chemistry , aryl , alkyl
A family of pincer-ligated cobalt complexes has been synthesized and are active for the catalytic C-H borylation of heterocycles and arenes. The cobalt catalysts operate with high activity and under mild conditions and do not require excess borane reagents. Up to 5000 turnovers for methyl furan-2-carboxylate have been observed at ambient temperature with 0.02 mol % catalyst loadings. A catalytic cycle that relies on a cobalt(I)-(III) redox couple is proposed.