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Macro Approach and Fuzzy Modeling of Entrapped Biocatalyst
Author(s) -
Ruggeri Bernardo,
Sassi Guido,
Bosco Francesca
Publication year - 2000
Publication title -
biotechnology progress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 129
eISSN - 1520-6033
pISSN - 8756-7938
DOI - 10.1021/bp9901264
Subject(s) - biomass (ecology) , fuzzy logic , macro , biological system , matrix (chemical analysis) , chemistry , ethanol , calcium alginate , biochemical engineering , mathematics , computer science , chromatography , calcium , biochemistry , biology , engineering , organic chemistry , artificial intelligence , agronomy , programming language
The interactions between a strain of Saccharomyces cerevisiae and an alginate matrix are investigated to ascertain the main factors affecting the bioreaction evolution. During the tests several parameters (glucose, ethanol, calcium ion and biomass concentration, pH, and alginate bed diameter) were evaluated, coupled with microscopic investigation inside the beads to determine the spatial biomass distribution. A detailed analysis of macro parameters and a correlation among them are proposed using a fuzzy algorithm. A global two‐step fuzzy model results in which biomass distribution inside the beads is represented as a hidden parameter.