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Flow Optimization in a Class of Enzymatic Plug‐Flow Reactor
Author(s) -
Figueroa Abel R. Castro,
Talavera H. José,
Colominas A. Maritza
Publication year - 1997
Publication title -
biotechnology progress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 129
eISSN - 1520-6033
pISSN - 8756-7938
DOI - 10.1021/bp9600905
Subject(s) - plug flow , plug flow reactor model , flow (mathematics) , packed bed , hydrolysis , mechanics , lactose , chemistry , class (philosophy) , degradation (telecommunications) , chromatography , materials science , thermodynamics , chemical engineering , mathematics , mathematical optimization , computer science , physics , continuous stirred tank reactor , organic chemistry , engineering , artificial intelligence , telecommunications
A vertical cylindrical packed‐bed plug‐flow reactor employed for a substance degradation is modeled. The question of its best performance is mathematically formulated, and the existence of the corresponding optimal flow axial velocity is proven. A way to compute this optimal velocity is exhibited as well. Results are obtained under a rather general hypothesis on the reaction velocity: it may be applied to first‐ and second‐order reactions, Michelis−Menten reactions, and others. An application to lactose hydrolysis on a β‐galactosidase‐immobilized chitosan bed is presented.