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Secret Signatures Inside Genomic DNA
Author(s) -
Arita Masanori,
Ohashi Yoshiaki
Publication year - 2004
Publication title -
biotechnology progress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 129
eISSN - 1520-6033
pISSN - 8756-7938
DOI - 10.1021/bp049917i
Subject(s) - bacillus subtilis , genomic dna , watermark , dna , computational biology , simple (philosophy) , biology , genetics , bacteria , computer science , artificial intelligence , philosophy , embedding , epistemology
Abstract A simple, practical method to watermark short trademarks or signatures into genomic DNA is introduced. Since the marking method is biologically innocuous, it can be applied to all commercialized bacteria to help establish brand names for the engineered strains and to resolve legal disputes regarding gene‐related patents. The first such strain of Bacillus subtilis is engineered and is ready to be distributed.