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Perspectives for the Industrial Enzymatic Production of Glycosides
Author(s) -
de Roode B. Mattheus,
Franssen Maurice C. R.,
Padt Albert van der,
Boom Remko M.
Publication year - 2003
Publication title -
biotechnology progress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 129
eISSN - 1520-6033
pISSN - 8756-7938
DOI - 10.1021/bp030038q
Subject(s) - glycoside , bioreactor , production (economics) , chemistry , biochemical engineering , food industry , chemical industry , microbiology and biotechnology , pulp and paper industry , organic chemistry , food science , biology , engineering , economics , macroeconomics
Glycosides are of commercial interest for industry in general and specifically for the pharmaceutical and food industry. Currently chemical preparation of glycosides will not meet EC food regulations, and therefore chemical preparation of glycosides is not applicable in the food industry. Thus, enzyme‐catalyzed reactions are a good alternative. However, until now the low yields obtained by enzymatic methods prevent the production of glycosides on a commercial scale. Therefore, high yields should be established by a combination of optimum reaction conditions and continuous removal of the product. Unfortunately, a bioreactor for the commercial scale production of glycosides is not available. The aim of this article is to discuss the literature with respect to enzymatic production of glycosides and the design of an industrially viable bioreactor system.