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Kinetic Study on the Enzymatic Resolution of Homophenylalanine Ester Using Ionic Liquids
Author(s) -
Zhao Hua,
Luo Robert G.,
Malhotra Sanjay V.
Publication year - 2003
Publication title -
biotechnology progress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 129
eISSN - 1520-6033
pISSN - 8756-7938
DOI - 10.1021/bp025721b
Subject(s) - ionic liquid , kinetic resolution , chemistry , solvent , resolution (logic) , amino acid , enzyme , solvent polarity , biocatalysis , enantiomer , organic chemistry , polarity (international relations) , ionic bonding , kinetic energy , enantioselective synthesis , catalysis , biochemistry , ion , artificial intelligence , computer science , cell , physics , quantum mechanics
Two ionic liquids (ILs) were investigated as novel media for the enzymatic resolution of amino acid ester to obtain enantiomeric amino acid homophenylalanine. The effects of solvent nature, polarity, and concentration on the kinetic resolution were investigated. With change in solvent concentration, a systematic study shows that an improved enzyme activity can be obtained by adjusting these solvent parameters.