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Model‐Based Optimization of Equipment and Control for Heat Flux Measurements in a Laboratory Fermentor
Author(s) -
Van Kleeff Bastiaan H. A.,
Kuenen J. Gijs,
Honderd Ger,
Heijnen Sef J.
Publication year - 1995
Publication title -
biotechnology progress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 129
eISSN - 1520-6033
pISSN - 8756-7938
DOI - 10.1021/bp00035a005
Subject(s) - heat flux , work (physics) , standard deviation , process engineering , computer science , flux (metallurgy) , environmental science , mechanical engineering , materials science , heat transfer , mechanics , engineering , mathematics , statistics , physics , metallurgy
The measurement of microbially‐produced heat in standard laboratory fermentors was studied with the help of a mathematical model describing the heat flows. The improvements that were indicated by the modeling work were implemented in the experimental setup. Tests showed that both the standard deviation in the heat measurement and the response time for the experimental setup improved through use of the modeling results.