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A Correlation for the Effective Strength of Escherichia coli during Homogenization
Author(s) -
Middelberg Anton P. J.,
O'Neill Brian K.
Publication year - 1993
Publication title -
biotechnology progress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 129
eISSN - 1520-6033
pISSN - 8756-7938
DOI - 10.1021/bp00019a017
Subject(s) - escherichia coli , homogenization (climate) , correlation , microbiology and biotechnology , chemistry , mathematics , food science , biology , biochemistry , gene , ecology , geometry , biodiversity
A new model for high‐pressure homogenization has been previously developed. A key model parameter, the mean effective cell strength, can be correlated with average cell length and peptidoglycan cross‐linkage. In this article, we develop a correlation for mean effective strength based on a statistical thermodynamic approach to fracture. The final correlation provides an unbiased estimate. While it offers no numerical advantage over a previous empirical correlation, it is based on a modeling approach and an understanding of wall structure. The variable groupings are therefore justifiable.