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Kinetics of Peroxidase Production by Streptomyces viridosporus and Recombinant Streptomyces lividans
Author(s) -
Korus Roger A,
Lodha Sanjay J,
Adhi Tri P,
Crawford Don L.
Publication year - 1991
Publication title -
biotechnology progress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.572
H-Index - 129
eISSN - 1520-6033
pISSN - 8756-7938
DOI - 10.1021/bp00012a005
Subject(s) - peroxidase , streptomyces , streptomycetaceae , recombinant dna , biology , actinomycetales , plasmid , biochemistry , chemistry , enzyme , genetics , gene , bacteria
The production of peroxidases by Streptomyces viridosporus T7A and recombinant Streptomyces lividans TK64.1 was characterized in stirred tank fermentors. The rate of peroxidase production was strongly growth associated with plasmid‐coded S. lividans , in contrast to chromosome‐coded S. viridosporus , where peroxidase production was proportional to cell mass rather than cell growth rate. A modified form of the logistic equation gave a good fit to the experimenal data for cell growth and peroxidase formation.