Therapeutic Assessment of Targeting ASNS Combined with l -Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms
Author(s) -
Verena Apfel,
Damien Bégué,
Valentina Cordoʹ,
Laura Holzer,
Laetitia Martinuzzi,
Alexandra Buhles,
Gráinne Kerr,
Inês Amorim Monteiro Barbosa,
Ulrike Naumann,
Michelle Piquet,
David A. Ruddy,
Andreas Weiss,
Stéphane Ferretti,
Reinaldo Almeida,
Débora Bonenfant,
Luca Tordella,
Giorgio Giacomo Galli
Publication year - 2021
Publication title -
acs pharmacology and translational science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.271
H-Index - 10
ISSN - 2575-9108
DOI - 10.1021/acsptsci.0c00196
Subject(s) - cancer research , asparaginase , gene silencing , synthetic lethality , asparagine synthetase , asparagine , biology , transcriptome , in vivo , melanoma , integrated stress response , leukemia , mutant , immunology , biochemistry , genetics , enzyme , gene , gene expression , lymphoblastic leukemia , translation (biology) , messenger rna
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