Open AccessQuantitative Systems Pharmacology Modeling of PBMC-Humanized Mouse to Facilitate Preclinical Immuno-oncology Drug Development
Author(s) -
Huilin Ma,
Minu Pilvankar,
Jun Wang,
Craig Giragossian,
Aleksander S. Popel
Publication year - 2020
Publication title -
acs pharmacology and translational science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.271
H-Index - 10
ISSN - 2575-9108
DOI - 10.1021/acsptsci.0c00178
Subject(s) - medicine , systems pharmacology , immunotherapy , immune system , cancer research , peripheral blood mononuclear cell , cytokine , pharmacology , in vivo , t cell , drug development , pharmacokinetics , cancer immunotherapy , humanized mouse , drug , immunology , in vitro , biology , biochemistry , microbiology and biotechnology
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