Open AccessMn(III)-Mediated C–H Phosphorylation of Indazoles with Dialkyl Phosphites
Author(s) -
Payel Ghosh,
Susmita Mondal,
Alakananda Hajra
Publication year - 2019
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.9b01121
Subject(s) - phosphorylation , chemistry , medicinal chemistry , stereochemistry , biochemistry
A direct and efficient Mn(III) acetate-mediated phosphorylation of 2 H -indazoles with dialkyl phosphites has been achieved under mild reaction conditions. A series of phosphorylated products with a wide range of functional groups were obtained in moderate to good yields. A radical mechanism has been proposed for the present protocol.
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