Mitochondria-Targeted New Blue Light-Emitting Fluorescent Molecular Probe | Zendy

Saswat Mohapatra | Zendy; Gaurav Das | Zendy; Chirantan Kar | Zendy; Masashi Nitani | Zendy; Yutaka Ie | Zendy; Yoshio Aso | Zendy; Surajit Ghosh | Zendy

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Mitochondria-Targeted New Blue Light-Emitting Fluorescent Molecular Probe

Author(s) -

Saswat Mohapatra,

Gaurav Das,

Chirantan Kar,

Masashi Nitani,

Yutaka Ie,

Yoshio Aso,

Surajit Ghosh

Publication year - 2019

Publication title -

acs omega

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 0.779

H-Index - 40

ISSN - 2470-1343

DOI - 10.1021/acsomega.8b03331

Subject(s) - fluorescence , organelle , mitochondrion , biophysics , intracellular , chemistry , blue light , fluorescence microscope , microbiology and biotechnology , biochemistry , biology , materials science , optics , optoelectronics , physics

Discovery of a nontoxic fluorescent molecular probe to "light up" specific cellular organelles is extremely essential to understand dynamics of intracellular components. Here, we report a new nontoxic mitochondria-targeted linear bithiazole compound, containing trifluoroacetyl terminal groups, which emits intense blue fluorescence and stained mitochondria of various cells. Interestingly, the power of fluorescence is completely off when the bithiazole unit is stapled by a carbonyl bridge.

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