Zinc and Magnesium Complexes Bearing Oxazoline-Derived Ligands and Their Application for Ring Opening Polymerization of Cyclic Esters

A family of different substituents aza(oxazoline) ligand-based zinc and magnesium complexes were synthesized. These complexes can catalyze ring opening polymerization of ε-caprolactone (ε-CL) and lactide (LA) to produce poly-ε-caprolactone and polylactide with good conversions. Polymerization studies showed that the zinc complexes 1a - 4a had moderate activity toward LA and ε-CL polymerization. In situ IR spectroscopy research of zinc complexes showed that the N-donor group-substituted complexes had higher activity than that of the O-ether donor group. The substituted analogies and the flexibility of the amino backbone had a distinct influence on the activity of LA and ε-CL polymerization. The alternates of zinc with magnesium produced complexes 5a - 8a , which achieved an obviously increased polymerization activity. Among these magnesium complexes, 7a showed the highest activity in the polymerization of LA. At [M]/[cat] = 1000, the reaction progress was stabilized in 5 min with up to 97% conversion of a monomer at ambient temperature.