Oxidation-Responsive, EuII/III-Based, Multimodal Contrast Agent for Magnetic Resonance and Photoacoustic Imaging | Zendy

Lina A. Basal | Zendy; Yan Yan | Zendy; Yimin Shen | Zendy; E. Mark Haacke | Zendy; Mohammad Mehrmohammadi | Zendy; Matthew J. Allen | Zendy

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Oxidation-Responsive, Eu^II/III-Based, Multimodal Contrast Agent for Magnetic Resonance and Photoacoustic Imaging

Author(s) -

Lina A. Basal,

Yan Yan,

Yimin Shen,

E. Mark Haacke,

Mohammad Mehrmohammadi,

Matthew J. Allen

Publication year - 2017

Publication title -

acs omega

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.779

H-Index - 40

ISSN - 2470-1343

DOI - 10.1021/acsomega.6b00514

Subject(s) - magnetic resonance imaging , photoacoustic imaging in biomedicine , nuclear magnetic resonance , contrast (vision) , resonance (particle physics) , saturation (graph theory) , materials science , chemistry , physics , optics , atomic physics , radiology , medicine , mathematics , combinatorics

We report, for the first time, a multimodal, oxidation-responsive contrast agent for magnetic resonance imaging and photoacoustic imaging that uses the differences in the properties between Eu in the +2 and +3 oxidation states. The enhancement of contrast in T 1 -weighted magnetic resonance and photoacoustic imaging was observed in the +2 but not in the +3 oxidation state, and the complex is a known chemical exchange saturation transfer agent for magnetic resonance imaging in the +3 oxidation state.

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