Open AccessDiscovery of Potent Glucokinase and PPARγ Dual-Target Agonists through an Innovative Scheme for Regioselective Modification of Silybin
Author(s) -
Zhipeng Zhang,
Meng Yang,
Wei Zhan,
Mei Yu,
Shite Gao,
Yue-Jiao Wu,
S. X. Du
Publication year - 2022
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.1c06778
Subject(s) - transactivation , chemistry , regioselectivity , glucokinase , agonist , silybum marianum , pharmacology , stereochemistry , biochemistry , enzyme , receptor , biology , medicine , transcription factor , gene , traditional medicine , catalysis