Open AccessDetailed Analytical Characterization of a Bispecific IgG1 CrossMab Antibody of the Knob-into-Hole Format Applying Various Stress Conditions Revealed Pronounced Stability
Author(s) -
Ingrid Grunert,
Katrin Heinrich,
Juliane Ernst,
Michael Hingar,
Alexandre Briguet,
Michael Leiß,
Manfred Wuhrer,
Dietmar Reusch,
Patrick Bulau
Publication year - 2022
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.1c06305
Subject(s) - deamidation , chemistry , antibody , bispecific antibody , epitope , isomerization , size exclusion chromatography , stress (linguistics) , computational biology , biophysics , biochemistry , monoclonal antibody , enzyme , biology , immunology , linguistics , philosophy , catalysis