Open AccessProteomic Changes in the Monolayer and Spheroid Melanoma Cell Models of Acquired Resistance to BRAF and MEK1/2 Inhibitors
Author(s) -
Ramón Martínez,
Weiliang Huang,
Heather V. Buck,
Samantha Rea,
Amy Defnet,
Maureen A. Kane,
Paul Shapiro
Publication year - 2022
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.1c05361
Subject(s) - mapk/erk pathway , melanoma , spheroid , cancer research , kinase , phosphorylation , protein kinase a , downregulation and upregulation , mek inhibitor , biology , microbiology and biotechnology , chemistry , cell culture , biochemistry , genetics , gene