Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation
Author(s) -
Duong Tien Anh,
Hai PhamThe,
Le D. Huy,
Hoang B. Ngoc,
Trinh T. M. Ngoc,
Do Thi Mai Dung,
Eun Jeong Park,
In K. Song,
Jong Soon Kang,
JooHee Kwon,
Trương Thanh Tùng,
SangBae Han,
NguyenHai Nam
Publication year - 2021
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.0c05870
Subject(s) - cytotoxicity , histone deacetylase , chemistry , stereochemistry , docking (animal) , ic50 , hdac8 , moiety , inhibitory postsynaptic potential , vorinostat , hdac1 , biochemistry , histone , in vitro , biology , medicine , nursing , neuroscience , gene
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