Laquinimod Prevents Adipogenesis and Obesity by Down-Regulating PPAR-γ and C/EBPα through Activating AMPK
Author(s) -
Guang Wang,
Bing Wu,
Lening Zhang,
Yang Cui,
Bo Zhang,
Heyuan Wang
Publication year - 2020
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.0c02525
Subject(s) - adipogenesis , oil red o , ampk , sterol regulatory element binding protein , adipose tissue , endocrinology , medicine , adipocyte , glucose transporter , glut4 , 3t3 l1 , white adipose tissue , chemistry , triglyceride , peroxisome proliferator activated receptor , protein kinase a , biology , biochemistry , receptor , kinase , cholesterol , sterol , insulin
obesity is defined as excessive accumulation of adipose tissues and is becoming one of the main global severe public health issues. The present study aims to investigate the anti-adipogenesis of laquinimod and the underlying mechanism.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom