Open AccessT1–T2 Dual-Modal Magnetic Resonance Imaging: From Molecular Basis to Contrast Agents
Author(s) -
Zijian Zhou,
Ruiliang Bai,
Jeeva Munasinghe,
Zheyu Shen,
Liming Nie,
Xiaoyuan Chen
Publication year - 2017
Publication title -
acs nano
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.554
H-Index - 382
eISSN - 1936-086X
pISSN - 1936-0851
DOI - 10.1021/acsnano.7b03075
Subject(s) - magnetic resonance imaging , medical diagnosis , contrast (vision) , computer science , modal , nuclear magnetic resonance , artificial intelligence , radiology , medicine , physics , materials science , polymer chemistry
Multimodal imaging strategies integrating manifold images have improved our ability to diagnose, to guide therapy, and to predict outcomes. Magnetic resonance imaging (MRI) is among the most widely used imaging technique in the clinic and can enable multiparameter anatomical demonstration of diagnosis. Due to the inherent black-and-white production of MR images, however, MRI detection is largely hampered by the occurrence of false-positive diagnoses. In this Perspective, we introduce the paradigm of manipulating the multiparameter MRI, T 1 -T 2 dual-modal MRI, along with enhancement by specific contrast agents. We hope this discussion will promote emerging research interest in T 1 -T 2 dual-modal MRI and provoke the rational design of contrast agents for sophisticated MRI applications.