A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL
Author(s) -
Bingqi Tong,
Jessica N. Spradlin,
Luiz F. T. Novaes,
Erika Zhang,
Xirui Hu,
Malte Moeller,
Scott M. Brittain,
Lynn M. McGregor,
Jeffrey M. McKenna,
John A. Tallarico,
Markus Schirle,
Thomas J. Maimone,
Daniel K. Nomura
Publication year - 2020
Publication title -
acs chemical biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.899
H-Index - 111
eISSN - 1554-8937
pISSN - 1554-8929
DOI - 10.1021/acschembio.0c00348
Subject(s) - ubiquitin ligase , cereblon , dasatinib , ubiquitin , dna ligase , microbiology and biotechnology , chemistry , cancer research , biology , biochemistry , signal transduction , tyrosine kinase , gene
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