Inhibition of NRAS Signaling in Melanoma through Direct Depalmitoylation Using Amphiphilic Nucleophiles
Author(s) -
Hetika D. Vora,
Mai Johnson,
Roberto J. Brea,
Andrew K. Rudd,
Neal K. Devaraj
Publication year - 2020
Publication title -
acs chemical biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.899
H-Index - 111
eISSN - 1554-8937
pISSN - 1554-8929
DOI - 10.1021/acschembio.0c00222
Subject(s) - neuroblastoma ras viral oncogene homolog , melanoma , palmitoylation , cancer research , gtpase , biology , signal transduction , microbiology and biotechnology , mutation , cysteine , biochemistry , kras , gene , enzyme
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