Asymmetric Syntheses of (+)- and (−)-Collybolide Enable Reevaluation of kappa-Opioid Receptor Agonism
Author(s) -
Sophia L. Shevick,
Stephan M. Freeman,
Guanghu Tong,
Robin Russo,
Laura Bohn,
Ryan A. Shenvi
Publication year - 2022
Publication title -
acs central science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.893
H-Index - 76
eISSN - 2374-7951
pISSN - 2374-7943
DOI - 10.1021/acscentsci.2c00442
Subject(s) - agonist , agonism , κ opioid receptor , enantiomer , chemistry , stereochemistry , metabolite , pharmacology , partial agonist , receptor , biology , biochemistry , politics , political science , law
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