Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction | Zendy

Scott E. Guimond | Zendy; Courtney J. MycroftWest | Zendy; Neha S. Gandhi | Zendy; Julia A. Tree | Zendy; Thuy T. Le | Zendy; C. Mirella Spalluto | Zendy; María Victoria Humbert | Zendy; Karen R. Buttigieg | Zendy; Naomi S. Coombes | Zendy; Michael J. Elmore | Zendy; Matthew E. Wand | Zendy; Kristiyström | Zendy; Joanna Said | Zendy; Yin Xiang Setoh | Zendy; Alberto A. Amarilla | Zendy; Naphak Modhiran | Zendy; Julian D. J. Sng | Zendy; Mohit Chhabra | Zendy; Paul R. Young | Zendy; Daniel J. Rawle | Zendy; Marcelo A. Lima | Zendy; Edwin A. Yates | Zendy; Richard Karlsson | Zendy; Rebecca L. Miller | Zendy; YenHsi Chen | Zendy; Ieva Bagdonaite | Zendy; Zhang Yang | Zendy; James P. Stewart | Zendy; Dung Nguyen | Zendy; Stephen M. Laidlaw | Zendy; Edward Hammond | Zendy; Keith Dredge | Zendy; Tom Wilkinson | Zendy; Daniel Watterson | Zendy; Alexander A. Khromykh | Zendy; Andreas Suhrbier | Zendy; Miles W. Carroll | Zendy; Edward Trybala | Zendy; Tomas Bergström | Zendy; Vito Ferro | Zendy; Mark A. Skidmore | Zendy; Jeremy E. Turnbull | Zendy

Open Access

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction

Author(s) -

Scott E. Guimond,

Courtney J. MycroftWest,

Neha S. Gandhi,

Julia A. Tree,

Thuy T. Le,

C. Mirella Spalluto,

María Victoria Humbert,

Karen R. Buttigieg,

Naomi S. Coombes,

Michael J. Elmore,

Matthew E. Wand,

Kristiyström,

Joanna Said,

Yin Xiang Setoh,

Alberto A. Amarilla,

Naphak Modhiran,

Julian D. J. Sng,

Mohit Chhabra,

Paul R. Young,

Daniel J. Rawle,

Marcelo A. Lima,

Edwin A. Yates,

Richard Karlsson,

Rebecca L. Miller,

YenHsi Chen,

Ieva Bagdonaite,

Zhang Yang,

James P. Stewart,

Dung Nguyen,

Stephen M. Laidlaw,

Edward Hammond,

Keith Dredge,

Tom Wilkinson,

Daniel Watterson,

Alexander A. Khromykh,

Andreas Suhrbier,

Miles W. Carroll,

Edward Trybala,

Tomas Bergström,

Vito Ferro,

Mark A. Skidmore,

Jeremy E. Turnbull

Publication year - 2022

Publication title -

acs central science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.893

H-Index - 76

eISSN - 2374-7951

pISSN - 2374-7943

DOI - 10.1021/acscentsci.1c01293

Subject(s) - vero cell , heparan sulfate , virus , biology , biological activity , chemistry , virology , heparin , computational biology , in vitro , biochemistry

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